BDP5290 Inhibitor

Name: BDP5290 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752449
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752449

BDP5290 is a potent inhibitor of both ROCK and MRCK (IC50s of 5nM, 50nM, 10nM and 100nM for ROCK1, ROCK2, MRCKalpha and MRCKbeta, respectively.) More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BDP5290, Inhibitor

Full Product Name

BDP5290

Product Gene Name

BDP5290, inhibitor

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

371.82

Formula

C17H18ClN7O

CAS

1817698-21-7

Smiles

Clc1cn(nc1C(=O)Nc1cn[nH]c1-c1ccccn1)C1CCNCC1

Receptor (IC50)

ROCK1: 5nM
ROCK2: 50nM
MRCKalpha: 10nM
MRCKbeta: 100nM

Solubility

DMSO: 12.5mg/mL (33.62mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for BDP5290, inhibitor

Home; Cell Cycle/Checkpoint; ROCK

Product References and Citations for BDP5290, inhibitor

1. Unbekandt M, Croft D R, Crighton D, et al. A novel small-molecule MRCK inhibitor blocks cancer cell invasion[J]. Cell Communication and Signaling, 2014, 12 (1):54.
2. Gandalovi?ová A, et al. Migrastatics-Anti-metastatic and Anti-invasion Drugs: Promises and Challenges. Trends Cancer. 2017 Jun;3 (6):391-406.

Other Notes

Small volumes of BDP5290, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BDP5290 purchase

MBS5752449 is an inhibitor targeting BDP5290.