CU-CPT9b Inhibitor

Name: CU-CPT9b Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752450
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752450

CU-CPT9b is an antagonist of toll-like receptor 8 (TLR8; Kd = 21nM). It inhibits activation of NF- B induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7nM. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CU-CPT9b, Inhibitor

Full Product Name

CU-CPT9b

Product Gene Name

CU-CPT9b, inhibitor

Product Synonym Names

CU-CPT-9b; TLR8-specific antagonist 1

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

251.28

Formula

C16H13NO2

CAS

2162962-69-6

Smiles

Cc1cc(ccc1O)-c1ccnc2cc(O)ccc12

Receptor (IC50)

TLR8

Solubility

DMSO: 100mg/mL (397.96mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for CU-CPT9b, inhibitor

Home; Immunology/Inflammation; TLR

Product References and Citations for CU-CPT9b, inhibitor

1. Zhang S, Hu Z, Tanji H, et al. Small-molecule inhibition of TLR8 through stabilization of its resting state[J]. Nature Chemical Biology, 2017, 14 (1):58-64.

Other Notes

Small volumes of CU-CPT9b, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CU-CPT9b purchase

MBS5752450 is an inhibitor targeting CU-CPT9b.