AX20017 Inhibitor

Name: AX20017 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752459
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752459

AX20017 is a small-molecule protein kinase G (PknG) inhibitor (IC50 : 0.39uM). It acts by blocking the proliferation of M. tuberculosis. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AX20017, Inhibitor

Full Product Name

AX20017

Product Gene Name

AX20017, inhibitor

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

264.34

Formula

C13H16N2O2S

CAS

329221-38-7

Smiles

NC(=O)c1c(NC(=O)C2CC2)sc2CCCCc12

Receptor (IC50)

PknG: 0.39uM

Solubility

DMSO: 32mg/mL (121.06mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for AX20017, inhibitor

Home; Others

Product References and Citations for AX20017, inhibitor

1. Scherr N, Honnappa S, Kunz G, et al. Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis[J]. Proceedings of the National Academy of Sciences, 2007, 104 (29):12151-12156.
2. Rita Székely, Frigyes Wáczek, István Szabadkai, et al. A novel drug discovery concept for tuberculosis: Inhibition of bacterial and host cell signalling[J]. Immunology Letters, 2008, 116 (2):225-231.

Other Notes

Small volumes of AX20017, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AX20017 purchase

MBS5752459 is an inhibitor targeting AX20017.