BAY1125976 Inhibitor

Name: BAY1125976 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752461
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752461

BAY1125976 is an allosteric inhibitor of Akt1 and Akt2 (IC50s of 5.2 and 18nM, respectively, in a time-resolved FRET assay) More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BAY1125976, Inhibitor

Full Product Name

BAY1125976

Product Gene Name

BAY1125976, inhibitor

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

383.45

Formula

C23H21N5O

CAS

1402608-02-9

Smiles

NC(=O)c1ccc2nc(c(-c3ccccc3)n2n1)-c1ccc(cc1)C1(N)CCC1

Receptor (IC50)

Akt

Solubility

DMSO: 10.33mg/mL (26.94mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for BAY1125976, inhibitor

Home; Cytoskeletal Signaling; Akt; BAY1125976

Product References and Citations for BAY1125976, inhibitor

1. Politz O, Siegel F, B rfacker L, et al. BAY 1125976, a selective allosteric AKT1/2 inhibitor exhibits high efficacy on AKT signaling-dependent tumor growth in mouse models[J]. International Journal of Cancer, 2016, 140 (2):449-459.

Other Notes

Small volumes of BAY1125976, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BAY1125976 purchase

MBS5752461 is an inhibitor targeting BAY1125976.