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Dihexa Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752512

Dihexa is an activator of the hepatocyte growth factor/c-Met (HGF/c-Met) system,it binds to HGF (Kd = 65 pM),and an analog of the peptide angiotensin IV. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Dihexa, Inhibitor
Full Product Name
Dihexa
Product Synonym Names
PNB-0408; N-hexanoic-Try-Ile-(6)-amino hexanoic amide; Hexanoyl-Tyr-Ile-Ahx-NH2
Form/Format
Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
504.66
Formula
C27H44N4O5
CAS
1401708-83-5
Smiles
CCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCCCCCC(N)=O
Receptor (IC50)
HGF: 65pM (kd)
Solubility
DMSO: 30mg/mL (59.45mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Structure of Dihexa, inhibitor

Dihexa Inhibitor – Cat# MBS5752512

Product References and Citations for Dihexa, inhibitor

1. Mccoy A T, Benoist C C, Wright J W, et al. Evaluation of Metabolically Stabilized Angiotensin IV Analogs as Procognitive/Antidementia Agents[J]. Journal of Pharmacology and Experimental Therapeutics, 2013, 344 (1):141-154.
2. Benoist C C, Kawas L H, Zhu M, et al. The Procognitive and Synaptogenic Effects of Angiotensin IV-Derived Peptides Are Dependent on Activation of the Hepatocyte Growth Factor/c-Met System[J]. Journal of Pharmacology and Experimental Therapeutics, 2014, 351 (2):390-402.

Other Notes

Small volumes of Dihexa, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Dihexa purchase

MBS5752512 is an inhibitor targeting Dihexa.
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