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WT-161 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752517

MBS5752517 is an inhibitor targeting WT-161. WT161 is a potent and selective inhibitor of HDAC6 (IC50:0.40nM). More details

Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
WT-161, Inhibitor
Full Product Name
WT-161
Product Gene Name
Form/Format
Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
458.55
Formula
C27H30N4O3
CAS
1206731-57-8
Smiles
ONC(=O)CCCCCCC(=O)N\N=C\c1ccc(cc1)N(c1ccccc1)c1ccccc1
Receptor (IC50)
HDAC6: 0.40nM
Solubility
DMSO: 100mg/mL (218.08mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for WT-161, inhibitor

Structure of WT-161, inhibitor

WT-161 Inhibitor – Cat# MBS5752517

Product References and Citations for WT-161, inhibitor

1. Hideshima T, Qi J, Paranal R M, et al. Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma[J]. Proceedings of the National Academy of Sciences, 2016:201608067.
2. Hideshima T, Mazitschek R, Qi J,et al.HDAC6 inhibitor WT161 downregulates growth factor receptors in breast cancer[J].Oncotarget. 2017 Jul 5;8 (46):80109-8012

Other Notes

Small volumes of WT-161, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for WT-161. It may not necessarily be applicable to this product.

Protein Family

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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