GSK547 Inhibitor

Name: GSK547 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752526
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752526

GSK547 is a highly selective and potent inhibitor of RIP1 kinase,inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GSK547, Inhibitor

Full Product Name

GSK547

Product Gene Name

GSK547, inhibitor

Product Synonym Names

GSK'547

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

396.39

Formula

C20H18F2N6O

CAS

2226735-55-1

Smiles

Fc1cc(F)cc(c1)[C@@H]1CC=NN1C(=O)C1CCN(CC1)c1cc(ncn1)C#N

Receptor (IC50)

RIP1

Solubility

DMSO: 125mg/mL (315.35mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for GSK547, inhibitor

Home; Apoptosis; TNF

Product References and Citations for GSK547, inhibitor

1. RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer[J]. Cancer Cell, 2018, 34 (5):757-774.e7.

Other Notes

Small volumes of GSK547, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSK547 purchase

MBS5752526 is an inhibitor targeting GSK547.