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all-trans-4-Oxoretinoic acid Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752531

MBS5752531 is an inhibitor targeting all-trans-4-Oxoretinoic acid. All-trans-4-Oxoretinoic acid is an active metabolite of vitamin A. More details

Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
all-trans-4-Oxoretinoic acid, Inhibitor
Full Product Name
all-trans-4-Oxoretinoic acid
Product Synonym Names
all-trans 4-Keto Retinoic Acid
Form/Format
Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
314.4
Formula
C20H26O3
CAS
38030-57-8
Smiles
CC(\C=C\C1=C(C)C(=O)CCC1(C)C)=C/C=C/C(C)=C/C(O)=O
Receptor (IC50)
Human Endogenous Metabolite
Solubility
DMSO: 150mg/mL (477.07mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product References and Citations for all-trans-4-Oxoretinoic acid, inhibitor

1. Eckhoff C, Nau H. Identification and quantitation of all-trans- and 13-cis-retinoic acid and 13-cis-4-oxoretinoic acid in human plasma[J].J Lipid Res. 1990 Aug;31 (8):1445-54.
2. Topletz A R, Tripathy S, Foti R S, et al. Induction of CYP26A1 by Metabolites of Retinoic Acid: Evidence That CYP26A1 Is an Important Enzyme in the Elimination of Active Retinoids[J]. Molecular Pharmacology, 2015, 87 (3):430-441.

Other Notes

Small volumes of all-trans-4-Oxoretinoic acid, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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