360A Inhibitor

Name: 360A Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752532
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752532

360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay (IC50 : 300nM). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

360A, Inhibitor

Full Product Name

360A

Product Gene Name

360A, inhibitor

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

449.5

Formula

C27H23N5O2

CAS

794458-56-3

Smiles

C[n+]1cc(NC(=O)c2cccc(n2)C(=O)Nc2c[n+](C)c3ccccc3c2)cc2ccccc12

Receptor (IC50)

Telomerase: 300nM

Solubility

(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for 360A, inhibitor

Home; DNA Damage/DNA Repair; Telomerase

Product References and Citations for 360A, inhibitor

1. Hwang I, Mailliet P, Hossard V, et al. Investigating the Effect of Mono- and Dimeric 360A G-Quadruplex Ligands on Telomere Stability by Single Telomere Length Analysis (STELA)[J]. Molecules, 2019, 24 (3).
2. Pennarun Galle, Christine G, Hoffschir Franoise, et al. Role of ATM in the telomere response to the G-quadruplex ligand 360A[J]. Nucleic Acids Research (5):5.

Other Notes

Small volumes of 360A, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 360A purchase

MBS5752532 is an inhibitor targeting 360A.