JNJ-5207852 Inhibitor

Name: JNJ-5207852 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752534
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752534

JNJ-5207852 is a novel, non-imidazole histamine H3 receptor antagonist, with high affinity at the rat (pKi=8.9) and human (pKi=9.24) H3 receptor. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

JNJ-5207852, Inhibitor

Full Product Name

JNJ-5207852

Product Gene Name

JNJ-5207852, inhibitor

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

316.48

Formula

C20H32N2O

CAS

398473-34-2

Smiles

C(COc1ccc(CN2CCCCC2)cc1)CN1CCCCC1

Receptor (IC50)

rat H3R: 8.9 (pKi)
human H3R: 9.24 (pKi)

Solubility

DMSO: 77.5mg/mL (244.88mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for JNJ-5207852, inhibitor

Home; GPCR/G Protein; Histamine Receptor

Product References and Citations for JNJ-5207852, inhibitor

1. Esbenshade T A, Browman K E, Bitner R S, et al. The histamine H3 receptor: an attractive target for the treatment of cognitive disorders[J]. 2008, 154 (6):1166-1181.
2. Abuhamdah R M A, Ruan V R, Lethbridge N L, et al. Effects of methimepip and JNJ-5207852 in Wistar rats exposed to an open-field with and without object and in Balb/c mice exposed to a radial-arm maze[J]. Frontiers in Systems Neuroscience, 2012, 6.

Other Notes

Small volumes of JNJ-5207852, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for JNJ-5207852 purchase

MBS5752534 is an inhibitor targeting JNJ-5207852.