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10beta,17beta-dihydroxyestra-1,4-dien-3-one Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752582

10beta,17beta-dihydroxyestra-1,4-dien-3-one is a brain-targeting bioprecursor prodrug of the main human estrogen, 17beta-estradiol. It alleviates hot flushes in rat models of thermoregulatory dysfunction of the brain. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
10beta,17beta-dihydroxyestra-1,4-dien-3-one, Inhibitor
Full Product Name
10beta,17beta-dihydroxyestra-1,4-dien-3-one
Product Synonym Names
DHED
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
288.38
Solubility
DMSO: 250mg/mL (866.91mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C18H24O3
SMILES
C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(O)[C@@]3([H])CC2)=O
CAS Number
549-02-0
Target & IC50
Others

Structure of 10beta,17beta-dihydroxyestra-1,4-dien-3-one, inhibitor

10beta,17beta-dihydroxyestra-1,4-dien-3-one Inhibitor – Cat# MBS5752582

Product References and Citations for 10beta,17beta-dihydroxyestra-1,4-dien-3-one, inhibitor

Merchenthaler I, et al. treatment,with an orally bioavailable prodrug of 17beta-estradiol alleviates hot flushes without hormonal effects in the periphery. Sci Rep. 2016 Aug 1;6:30721.
Merchenthaler I, et al. treatment,with an orally bioavailable prodrug of 17beta-estradiol alleviates hot flushes without hormonal effects in the periphery. Sci Rep. 2016 Aug 1;6:30721.

Other Notes

Small volumes of 10beta,17beta-dihydroxyestra-1,4-dien-3-one, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 10beta,17beta-dihydroxyestra-1,4-dien-3-one purchase

MBS5752582 is an inhibitor targeting 10beta,17beta-dihydroxyestra-1,4-dien-3-one.
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