2',3'-cGAMP sodium Inhibitor

Name: 2',3'-cGAMP sodium Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752592
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752592

2',3'-cGAMP sodium is an endogenous cGAMP in mammalian cells. It binds to STING with a high affinity and is a potent inducer of IFN-beta. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

2',3'-cGAMP sodium, Inhibitor

Full Product Name

2',3'-cGAMP sodium

Product Synonym Names

2'-3'-cyclic GMP-AMP sodium

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

718.37

Solubility

DMSO: 12.5mg/mL (17.40mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C20H22N10Na2O13P2

SMILES

OC1([H])[C@](OP(OC[C@](O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@@H]4O)([H])[C@@]4([H])O5)(O[Na])=O)([H])[C@H](N6C(NC(N)=NC7=O)=C7N=C6)O[C@]1([H])COP5(O[Na])=O

Target & IC50

Human Endogenous Metabolite

Product Categories/Family for 2',3'-cGAMP sodium, inhibitor

Metabolic Enzyme/Protease

Product References and Citations for 2',3'-cGAMP sodium, inhibitor

Zhang X, et al. Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING. Mol Cell. 2013 Jul 25;51(2):226-35.

Other Notes

Small volumes of 2',3'-cGAMP sodium, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 2',3'-cGAMP sodium purchase

MBS5752592 is an inhibitor targeting 2',3'-cGAMP sodium.