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2-Methyl-5-HT Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752596

2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
2-Methyl-5-HT, Inhibitor
Full Product Name
2-Methyl-5-HT
Product Synonym Names
2-Methyl-5-hydroxytryptamine
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
190.24
Solubility
DMSO: 125mg/mL (657.06mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C11H14N2O
SMILES
OC1=CC2=C(NC(C)=C2CCN)C=C1
CAS Number
78263-90-8
Target & IC50
5-HT3 Receptor
In Vitro
2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) significantly decreases time of immobility thus showing anti-depressive-like effects[1].

Product References and Citations for 2-Methyl-5-HT, inhibitor

Sumaya IC, et al. Differential effects of a short-term high-fat diet in an animal model of depression in rats treated with the 5-HT3 receptor antagonist, ondansetron, the 5-HT3 receptor agonist, 2-methyl-5-HT, and the SSRI, fluoxetine. Pharmacol Biochem Behav. 2016 May;144:78-84.
Sumaya IC, et al. Differential effects of a short-term high-fat diet in an animal model of depression in rats treated with the 5-HT3 receptor antagonist, ondansetron, the 5-HT3 receptor agonist, 2-methyl-5-HT, and the SSRI, fluoxetine. Pharmacol Biochem Behav. 2016 May;144:78-84.

Other Notes

Small volumes of 2-Methyl-5-HT, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 2-Methyl-5-HT purchase

MBS5752596 is an inhibitor targeting 2-Methyl-5-HT.
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