4-Diethylaminobenzaldehyde Inhibitor

4-Diethylaminobenzaldehyde is a reversible aldehyde dehydrogenase (ALDH) inhibitor (Ki: 4nM for ALDH1). It displays a potent anti-androgenic effect (IC50: 1.71uM).

Luo M, et al. Diethylaminobenzaldehyde is a covalent, irreversible inactivator of ALDH7AACS Chem Biol. 2015 Mar 20;10(3):693-7.
Luo M, et al. Diethylaminobenzaldehyde is a covalent, irreversible inactivator of ALDH7A1. ACS Chem Biol. 2015 Mar 20;10(3):693-7.
Araki N, et al. Screening for androgen receptor activities in 253 industrial chemicals by in vitro reporter gene assays using AR-EcoScreen cells. Toxicol In Vitro. 2005 Sep;19(6):831-42.
Araki N, et al. Screening for androgen receptor activities in 253 industrial chemicals by in vitro reporter gene assays using AR-EcoScreen cells. Toxicol In Vitro. 2005 Sep;19(6):831-42.

Small volumes of 4-Diethylaminobenzaldehyde, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5752624 is an inhibitor targeting 4-Diethylaminobenzaldehyde.