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ADU-S100 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752669

MBS5752669 is an inhibitor targeting ADU-S100. ADU-S100 is an activator of stimulator of interferon genes (STING). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ADU-S100, Inhibitor
Full Product Name
ADU-S100
Product Gene Name
ADU-S100, inhibitor
Product Synonym Names
MIW815;mL RR-S2 CDA
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
690.54
Solubility
H2O: 50mg/mL (72.41mM) Need ultrasonic
DMSO: 2mg/mL (2.90mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C20H24N10O10P2S2
SMILES
OC1([H])[C@](O[P@](S)(OC[C@](O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@@H]4O)([H])[C@@]4([H])O5)=O)([H])[C@H](N6C7=NC=NC(N)=C7N=C6)O[C@]1([H])CO[P@]5(S)=O
CAS Number
1638241-89-0
Target & IC50
STING
In Vitro
A dose response of the ADU-S100 compound is performed in B16 tumor-bearing mice, which identifies an optimal antitumor dose level that also elicites maximum tumor antigen-specific CD8+ T cell responses, and improves long-term survival to 50%[1].

Product Categories/Family for ADU-S100, inhibitor

Immunology/Inflammation

Structure of ADU-S100, inhibitor

ADU-S100 Inhibitor – Cat# MBS5752669

Product References and Citations for ADU-S100, inhibitor

Corrales L, et al. Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity. Cell Rep. 2015 May 19;11(7):1018-30.
Corrales L, et al. Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity. Cell Rep. 2015 May 19;11(7):1018-30.

Other Notes

Small volumes of ADU-S100, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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