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Aglafoline Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752670

Aglafoline inhibits in a concentration-dependent manner the aggregation and ATP release reaction induced in washed rabbit platelets by PAF (platelet-activating factor). The IC50 values of Aglafoline on PAF (3.6nM)-induced platelet aggregation were about 50uM. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Aglafoline, Inhibitor
Full Product Name
Aglafoline
Product Synonym Names
Aglafolin; Rocaglamide U; (-)-Methyl rocaglate
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
492.52
Solubility
Ethanol: 100mg/mL (203.04mM) Need ultrasonic
DMSO: 21.43mg/mL (43.51mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C28H28O8
SMILES
O=C([C@H]([C@H]1C2=CC=CC=C2)[C@@H](O)[C@]3(O)[C@@]1(C4=CC=C(OC)C=C4)OC5=CC(OC)=CC(OC)=C35)OC
CAS Number
143901-35-3
Target & IC50
Others

Structure of Aglafoline, inhibitor

Aglafoline Inhibitor – Cat# MBS5752670

Product References and Citations for Aglafoline, inhibitor

Ko FN, et al. PAF antagonism in vitro and in vivo by aglafoline from Aglaia elliptifolia Merr. Eur J Pharmacol. 1992 Jul 21;218(1):129-35.
Ko FN, et al. PAF antagonism in vitro and in vivo by aglafoline from Aglaia elliptifolia Merr. Eur J Pharmacol. 1992 Jul 21;218(1):129-35.

Other Notes

Small volumes of Aglafoline, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Aglafoline purchase

MBS5752670 is an inhibitor targeting Aglafoline.
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