Angiotensin II TFA Inhibitor

Name: Angiotensin II TFA Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752695
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752695

Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity. More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Angiotensin II TFA, Inhibitor

Full Product Name

Angiotensin II (3-8), human TFA

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

888.93

Solubility

H2O: 50mg/mL (56.25mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C42H55F3N8O10

SMILES

O=C(O)C(F)(F)F.O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CNC=N2)C(N3[C@@H](CCC3)C(N[C@@H](CC4=CC=CC=C4)C(O)=O)=O)=O)=O)=O)[C@H](C(C)C)N

Target & IC50

Angiotensin AT1 receptor

In Vitro

In anesthetized rats, Human Angiotensin II (3-8) causes endothelium-dependent renal cortical vasodilatation. At doses up to 125pmol/kg, human Angiotensin II (3-8) is without any cardiovascular effects, but with doses of 1.25 and 12.5nMol/kg there are dose-dependent increases in mean arterial blood pressure and reductions in renal and mesenteric flows and vascular conductances.

Product Categories/Family for Angiotensin II TFA, inhibitor

Endocrinology/Hormones; RAAS

Product References and Citations for Angiotensin II TFA, inhibitor

Gardiner SM, et al. Regional haemodynamic effects of angiotensin II (3-8) in conscious rats. Br J Pharmacol. 1993 Sep;110(1):159-62.
Gardiner SM, et al. Regional haemodynamic effects of angiotensin II (3-8) in conscious rats. Br J Pharmacol. 1993 Sep;110(1):159-62.

Other Notes

Small volumes of Angiotensin II TFA, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Angiotensin II TFA purchase

MBS5752695 is an inhibitor targeting Angiotensin II TFA. Also known as Angiotensin II (3-8), human TFA.