AZ505 Inhibitor – Ditrifluoroacetate

Name: AZ505 Inhibitor; Ditrifluoroacetate; MyBioSource
Brand: MyBioSource
SKU: MBS5752745
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752745

AZ505 ditrifluoroacetate is an effective and selective SMYD2 inhibitor (IC50: 0.12uM). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AZ505 ditrifluoroacetate, Inhibitor

Full Product Name

AZ505 ditrifluoroacetate

Product Gene Name

AZ505, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

805.59

Solubility

DMSO: 125mg/mL (155.17mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C33H40Cl2F6N4O8

SMILES

O=C(N(C1CCCCC1)CCNCCC2=C(OCC(N3)=O)C3=C(O)C=C2)CCNCCC4=CC=C(Cl)C(Cl)=C4.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

CAS Number

1035227-44-1

Target & IC50

SMYD2: ic50 0.12uM

Product Categories/Family for AZ505, inhibitor

Chromatin/Epigenetic; Histone Methyltransferase

Product References and Citations for AZ505, inhibitor

Komatsu S, et al. Overexpression of SMYD2 contributes to malignant outcome in gastric cancer. Br J Cancer. 2015 Jan 20;112(2):357-64.
Komatsu S, et al. Overexpression of SMYD2 contributes to malignant outcome in gastric cancer. Br J Cancer. 2015 Jan 20;112(2):357-64.
Ferguson AD, et al. Structural basis of substrate methylation and inhibition of SMYDStructure. 2011 Sep 7;19(9):1262-73.
Ferguson AD, et al. Structural basis of substrate methylation and inhibition of SMYD2. Structure. 2011 Sep 7;19(9):1262-73.

Other Notes

Small volumes of AZ505, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AZ505 purchase

MBS5752745 is an inhibitor targeting AZ505. Also known as AZ505 ditrifluoroacetate.