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AZD4573 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752754

MBS5752754 is an inhibitor targeting AZD4573. AZD4573 is an effective and selective CDK9 inhibitor (IC50: More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AZD4573, Inhibitor
Full Product Name
AZD4573
Product Gene Name
AZD4573, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
429.94
Solubility
DMSO: 125mg/mL (290.74mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C22H28ClN5O2
SMILES
CC(=O)N[C@@H]1CCC[C@@H](C1)C(=O)Nc1cc(-c2cnn3CC(C)(C)Cc23)c(Cl)cn1
CAS Number
2057509-72-3
Target & IC50
CDK9: ic50 4nM
In Vitro
AZD4573 exhibits a short half-life in multiple species (less than one hour in dog, rat, and monkey) and good solubility for intravenous administration.

Product Categories/Family for AZD4573, inhibitor

Cell Cycle/Checkpoint; CDK

Structure of AZD4573, inhibitor

AZD4573 Inhibitor – Cat# MBS5752754

Product References and Citations for AZD4573, inhibitor

Bernard Barlaam, et al. Abstract 1650: Discovery of AZD4573, a potent and selective inhibitor of CDK9 that enables transient target engagement for the treatment,of hematologic malignancies. Cancer Research. July 2018. 78(13): Supplement.
Bernard Barlaam, et al. Abstract 1650: Discovery of AZD4573, a potent and selective inhibitor of CDK9 that enables transient target engagement for the treatment,of hematologic malignancies. Cancer Research. July 2018. 78(13): Supplement.

Other Notes

Small volumes of AZD4573, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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