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Bicyclomycin benzoate Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752796

Bicyclomycin benzoate, an antibiotic, exhibits activity against a broad spectrum of Gram-negative/Gram-positive bacteria. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Bicyclomycin benzoate, Inhibitor
Full Product Name
Bicyclomycin benzoate
Product Synonym Names
FR2054
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
406.39
Solubility
DMSO: 100mg/mL (246.07mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C19H22N2O8
SMILES
O[C@H]([C@](NC1=O)(OCCC2=C)C(N[C@]12O)=O)[C@@](C)(O)COC(C3=CC=CC=C3)=O
CAS Number
37134-40-0
Target & IC50
Others
In Vitro
After a single intramuscular dose of 50mg/kg in rats, Bicyclomycin has a low excretion rate. Bicyclomycin is well distributed in various tissues, and the highest concentration is observed in the kidney at 100mg/kg [4].

Product References and Citations for Bicyclomycin benzoate, inhibitor

Tanaka N, et al. Mechanism of action of bicyclomycin. J Antibiot (Tokyo). 1976 Feb;29(2):155-68.
Tanaka N, et al. Mechanism of action of bicyclomycin. J Antibiot (Tokyo). 1976 Feb;29(2):155-68.
Kohn H, et al. The molecular basis for the mode of action of bicyclomycin. Curr Drug Targets Infect Disord. 2005 Sep;5(3):273-95.
Kohn H, et al. The molecular basis for the mode of action of bicyclomycin. Curr Drug Targets Infect Disord. 2005 Sep;5(3):273-95.
Park HG, et al. Bicyclomycin and dihydrobicyclomycin inhibition kinetics of Escherichia coli rho-dependent transcription termination factor ATPase activity. Arch Biochem Biophys. 1995 Nov 10;323(2):447-54.
Park HG, et al. Bicyclomycin and dihydrobicyclomycin inhibition kinetics of Escherichia coli rho-dependent transcription termination factor ATPase activity. Arch Biochem Biophys. 1995 Nov 10;323(2):447-54.
Nishida M. et al. Bicyclomycin, a new antibiotic. IV. Absorption, excretion and tissue distribution. J Antibiot (Tokyo). 1972 Oct;25(10):594-601.
Nishida M. et al. Bicyclomycin, a new antibiotic. IV. Absorption, excretion and tissue distribution. J Antibiot (Tokyo). 1972 Oct;25(10):594-601.

Other Notes

Small volumes of Bicyclomycin benzoate, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Bicyclomycin benzoate purchase

MBS5752796 is an inhibitor targeting Bicyclomycin benzoate.
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