BRD4354 Inhibitor – BRD 4354 Ditrifluoroacetate

Name: BRD4354 Inhibitor; BRD 4354 Ditrifluoroacetate; MyBioSource
Brand: MyBioSource
SKU: MBS5752822
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752822

BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9 (IC50s: 0.85 and 1.88 uM). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BRD 4354 ditrifluoroacetate (BRD4354), Inhibitor

Full Product Name

BRD 4354 ditrifluoroacetate

Product Gene Name

BRD4354, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

610.93

Solubility

DMSO: 125mg/mL (204.61mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C25H25ClF6N4O5

SMILES

OC1=C2N=CC=CC2=C(Cl)C=C1C(N3CCN(CC)CC3)C4=CC=CN=C4.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

Target & IC50

HDAC5: ic50 0.85uM
HDAC9: ic50 1.88uM

Product Categories/Family for BRD4354, inhibitor

Chromatin/Epigenetic; HDAC; DNA Damage/DNA Repair

Product References and Citations for BRD4354, inhibitor

Boskovic ZV, ET AL. Inhibition of Zinc-Dependent Histone Deacetylases with a Chemically Triggered Electrophile. ACS Chem Biol. 2016 Jul 15;11(7):1844-51.
Boskovic ZV, ET AL. Inhibition of Zinc-Dependent Histone Deacetylases with a Chemically Triggered Electrophile. ACS Chem Biol. 2016 Jul 15;11(7):1844-51.

Other Notes

Small volumes of BRD4354, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BRD4354 purchase

MBS5752822 is an inhibitor targeting BRD4354. Also known as BRD 4354 ditrifluoroacetate.