Carebastine Inhibitor

Name: Carebastine Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752860
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752860

Carebastine, the active metabolite of Ebastine, is an antagonist of the histamine H receptor. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Carebastine, Inhibitor

Full Product Name

Carebastine

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

499.64

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C32H37NO4

SMILES

O=C(CCCN1CCC(OC(C2=CC=CC=C2)C3=CC=CC=C3)CC1)C4=CC=C(C=C4)C(C)(C(O)=O)C

CAS Number

90729-42-3

Target & IC50

H1 receptor

In Vitro

Carebastine inhibits VEGF-induced HPAEC and HUVEC proliferation, migration, and angiogenesis in a dose-dependent manner [1]. Carebastine suppresses the expression of macrophage migration inhibitory factor [2].

Product Categories/Family for Carebastine, inhibitor

GPCR/G Protein; Histamine Receptor; Immunology/Inflammation; Neuroscience

Product References and Citations for Carebastine, inhibitor

De Luisi A, et al. Anti-angiogenic activity of carebastine: a plausible mechanism affecting airway remodelling. Eur Respir J. 2009 Oct;34(4):958-66.
De Luisi A, et al. Anti-angiogenic activity of carebastine: a plausible mechanism affecting airway remodelling. Eur Respir J. 2009 Oct;34(4):958-66.
Zhao Y, et al. Carebastine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor. Clin Exp Dermatol. 2008 Nov;33(6):785-7.
Zhao Y, et al. Carebastine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor. Clin Exp Dermatol. 2008 Nov;33(6):785-7.

Other Notes

Small volumes of Carebastine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Carebastine purchase

MBS5752860 is an inhibitor targeting Carebastine.