CCI-006 Inhibitor

Name: CCI-006 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752876
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752876

CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells. It inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response in a subset of MLL-r leukemia… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CCI-006, Inhibitor

Full Product Name

CCI-006

Product Gene Name

CCI-006, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

332.33

Solubility

DMSO: 83.33mg/mL (250.74mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C15H12N2O5S

SMILES

COC(=O)C(\C#N)=C\c1ccc(o1)-c1ccc(cc1)S(N)(=O)=O

CAS Number

292053-42-0

Target & IC50

Mitochondria

Product Categories/Family for CCI-006, inhibitor

Metabolic Enzyme/Protease

Product References and Citations for CCI-006, inhibitor

Somers K, et al. A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction. Oncogene. 2019 Jan 22.
Somers K, et al. A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction. Oncogene. 2019 Jan 22.

Other Notes

Small volumes of CCI-006, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCI-006 purchase

MBS5752876 is an inhibitor targeting CCI-006.