CDC7-IN-1 Inhibitor

Name: CDC7-IN-1 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752885
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752885

Cdc7-IN-1 is a highly selective and ATP competitive inhibitor of Cdc7 kinase (IC50: 0.6nM at 1mM ATP). It potently inhibits Cdc7 activity in cancer cells and effectively induces cell death. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Cdc7-IN-1, Inhibitor

Full Product Name

Cdc7-IN-1

Product Gene Name

Cdc7-IN-1, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

409.82

Solubility

DMSO: 5.2mg/mL (12.69mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C21H16ClN3O4

SMILES

O=C1C(C(OCC)=O)=C(NC2=C(Cl)C=CC=C2)O/C1=C\C3=CNC4=C3C=CC=N4

CAS Number

1402055-25-7

Target & IC50

Cdc7, at 1mM ATP: ic50 0.6nM

Product Categories/Family for Cdc7-IN-1, inhibitor

Cell Cycle/Checkpoint; CDK

Product References and Citations for Cdc7-IN-1, inhibitor

Irie T, et al. Discovery of novel furanone derivatives as potent Cdc7 kinase inhibitors. Eur J Med Chem. 2017 Apr 21;130:406-418.
Irie T, et al. Discovery of novel furanone derivatives as potent Cdc7 kinase inhibitors. Eur J Med Chem. 2017 Apr 21;130:406-418.

Other Notes

Small volumes of Cdc7-IN-1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cdc7-IN-1 purchase

MBS5752885 is an inhibitor targeting Cdc7-IN-1.