CDDO-EA Inhibitor

Name: CDDO-EA Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752886
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752886

CDDO-EA is an activator of NF-E2 related factor 2/antioxidant response element (Nrf2/ARE). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CDDO-EA, Inhibitor

Full Product Name

CDDO-EA

Product Gene Name

CDDO-EA, inhibitor

Product Synonym Names

CDDO ethyl amide; TP319; RTA 405

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

518.73

Solubility

DMSO: 34mg/mL (65.54mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C33H46N2O3

SMILES

O=C1C(C#N)=C[C@@]2(C)[C@](CC[C@]([C@@]3(C)[C@@]4([H])[C@@]5([H])[C@@](CCC(C)(C)C5)(C(NCC)=O)CC3)(C)C2=CC4=O)([H])C1(C)C

CAS Number

932730-51-3

Target & IC50

Nrf2/ARE

Product Categories/Family for CDDO-EA, inhibitor

Immunology/Inflammation; Nrf2

Product References and Citations for CDDO-EA, inhibitor

Neymotin A, et al. Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis. Free Radic Biol Med. 2011 Jul 1;51(1):88-96.
Neymotin A, et al. Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis. Free Radic Biol Med. 2011 Jul 1;51(1):88-96.
Liby K, et al. The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice. Cancer Res. 2007 Mar 15;67(6):2414-9.
Liby K, et al. The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice. Cancer Res. 2007 Mar 15;67(6):2414-9.

Other Notes

Small volumes of CDDO-EA, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDDO-EA purchase

MBS5752886 is an inhibitor targeting CDDO-EA.