CDK4/6-IN-4 Inhibitor

Name: CDK4/6-IN-4 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752889
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752889

CDK4/6-IN-4 is a selective CDK4/6 inhibitor and the active metabolite of Abemaciclib. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CDK4/6-IN-4, Inhibitor

Full Product Name

CDK4/6-IN-4

Product Gene Name

CDK4/6-IN-4, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

522.59

Solubility

DMSO: 5mg/mL (9.57mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C27H32F2N8O

SMILES

OCC1=NC2=C(F)C=C(C3=NC(NC4=NC=C(CN5CCN(CC)CC5)C=C4)=NC=C3F)C=C2N1C(C)C

CAS Number

2138499-06-4

Target & IC50

CDK4

Product Categories/Family for CDK4/6-IN-4, inhibitor

Cell Cycle/Checkpoint; CDK

Product References and Citations for CDK4/6-IN-4, inhibitor

Richard Paul Beckmann, et al. Combination therapy with notch and cdk4/6 inhibitors for the treatment,of cancer. WO2017180389A1.
Richard Paul Beckmann, et al. Combination therapy with notch and cdk4/6 inhibitors for the treatment,of cancer. WO2017180389A1.

Other Notes

Small volumes of CDK4/6-IN-4, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDK4/6-IN-4 purchase

MBS5752889 is an inhibitor targeting CDK4/6-IN-4.