Ceftriaxone sodium salt Inhibitor

Solid. Powder

98.00%

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

600.56

DMSO: 50mg/mL (83.26mM) Need ultrasonic
H2O: 40mg/mL (66.60mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

C18H18N8Na2O7S32+

O=C(NN(C)C(SCC(CS[C@]1([H])[C@@H]2NC(/C(C3=CSC(N)=N3)=N\OC)=O)=C(C(O)=O)N1C2=O)=N4)C4=O.[Na+].[Na+]

74578-69-1

Others

Ceftriaxone inhibits bacterial cell wall synthesis by means of binding to the penicillin-binding proteins (PBPs). Inhibition of PBPs would in turn inhibit the transpeptidation step in peptidoglycan synthesis which is required for bacterial cell walls. Like other cephalosporins, ceftriaxone is bacteriocidal and exhibits time-dependent killing. Ceftriaxone is a stimulator of EAAT2 expression with neuroprotective effects in both in vitro and in vivo models based in part on its ability to inhibit neuronal cell death by glutamate excitotoxicity.