CGP20712A Inhibitor – CGP 20712 A

Name: CGP20712A Inhibitor; CGP 20712 A; MyBioSource
Brand: MyBioSource
SKU: MBS5752910
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752910

CGP 20712 A (CGP 20712 mesylate) is a highly selective antagonist of beta1-adrenoceptor (IC50: 0.7nM). It shows ~10,000-fold selectivity over beta2-adrenoceptors. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CGP 20712 A (CGP20712A), Inhibitor

Full Product Name

CGP 20712 A

Product Gene Name

CGP20712A, inhibitor

Product Synonym Names

CGP 20712 mesylate

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

590.57

Solubility

DMSO: 100mg/mL (169.33mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C24H29F3N4O8S

SMILES

O=C(N)C1=CC(OCCNCC(O)COC2=CC=C(C3=NC(C(F)(F)F)=CN3C)C=C2)=CC=C1O.CS(=O)(O)=O

CAS Number

105737-62-0

Target & IC50

beta1-adrenoceptor: ic50 0.7nM

In Vitro

In 8-day-old rats, pretreatment with 5mg/kg CGP 20712 A does not change the plasma ACTH response to insulin injection [3].

Product Categories/Family for CGP20712A, inhibitor

GPCR/G Protein; Adrenergic Receptor; Neuroscience

Product References and Citations for CGP20712A, inhibitor

Dooley DJ, et al. CGP 20712 A: a useful tool for quantitating beta 1- and beta 2-adrenoceptors. Eur J Pharmacol. 1986 Oct 14;130(1-2):137-9.
Dooley DJ, et al. CGP 20712 A: a useful tool for quantitating beta 1- and beta 2-adrenoceptors. Eur J Pharmacol. 1986 Oct 14;130(1-2):137-9.
Kitagawa Y, et al. Determination of beta-adrenoceptor subtype on rat isolated ventricular myocytes by use of highly selective beta-antagonists. Br J Pharmacol. 1995 Sep;116(1):1635-43.
Kitagawa Y, et al. Determination of beta-adrenoceptor subtype on rat isolated ventricular myocytes by use of highly selective beta-antagonists. Br J Pharmacol. 1995 Sep;116(1):1635-43.
Grino M, et al. Ontogeny of insulin-induced hypoglycemia stimulation of adrenocorticotropin secretion in the rat: role of catecholamines. Endocrinology. 1992 Dec;131(6):2763-8.
Grino M, et al. Ontogeny of insulin-induced hypoglycemia stimulation of adrenocorticotropin secretion in the rat: role of catecholamines. Endocrinology. 1992 Dec;131(6):2763-8.

Other Notes

Small volumes of CGP20712A, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CGP20712A purchase

MBS5752910 is an inhibitor targeting CGP20712A. Also known as CGP 20712 A.