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cis-Urocanic acid Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752925

cis-Urocanic acid is a 5-HT2A receptor agonist (Kd: 4.6nM). It is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
cis-Urocanic acid, Inhibitor
Full Product Name
cis-Urocanic acid
Product Synonym Names
(Z)-Urocanic acid; cis-UCA
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
138.12
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C6H6N2O2
SMILES
O=C(O)/C=C\C1=CN=CN1
CAS Number
7699-35-6
Target & IC50
5-HT2A Receptor

Product References and Citations for cis-Urocanic acid, inhibitor

Walterscheid JP, et al. Cis-urocanic acid, a sunlight-induced immunosuppressive factor, activates immune suppression via the 5-HT2A receptor. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17420-5.
Walterscheid JP, et al. Cis-urocanic acid, a sunlight-induced immunosuppressive factor, activates immune suppression via the 5-HT2A receptor. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17420-5.
Viiri J, et al. Cis-urocanic acid suppresses UV-B-induced interleukin-6 and -8 secretion and cytotoxicity in human corneal and conjunctival epithelial cells in vitro. Mol Vis. 2009 Sep 8;15:1799-805.
Viiri J, et al. Cis-urocanic acid suppresses UV-B-induced interleukin-6 and -8 secretion and cytotoxicity in human corneal and conjunctival epithelial cells in vitro. Mol Vis. 2009 Sep 8;15:1799-805.

Other Notes

Small volumes of cis-Urocanic acid, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS5752925 is an inhibitor targeting cis-Urocanic acid.
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