• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CXCR7 Inhibitor – Modulator 2

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752960

CXCR7 modulator 2 is a 7-type C-X-C chemokine receptor (CXCR7) modulator with a Ki of 13nM. More details

Please Inquire
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CXCR7 modulator 2, Inhibitor
Full Product Name
CXCR7 modulator 2
Product Gene Name
CXCR7, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
522.68
Solubility
DMSO: 250mg/mL (478.30mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C29H42N6O3
SMILES
O=C([C@@H]1[C@H](O2)CC[C@H]2C1)N3CCC([C@H](CC(N)=O)N4CCCN(C5=C(CC)C=CN6C5=NC=C6)CC4)CC3
CAS Number
2227426-37-9
Target & IC50
CXCR7: ic50 13nM (ki)
In Vitro
The administration of isoproterenol for 9 days will lead to the development of cardiac fibrosis. This is because the amount of collagen deposition detected by Pixirius red staining has increased by about 4 times relative to that of the control group. proven. treatment with CXCR7 modulator 2 can lead to a statistically significant reduction in cardiac fibrosis, thus demonstrating that CXCR7 modulator 2 has a protective effect on CXCR7 modulation in isoproterenol-induced cardiac injury.

Structure of CXCR7, inhibitor

CXCR7 Inhibitor – Cat# MBS5752960

Product References and Citations for CXCR7, inhibitor

Menhaji-Klotz E, et al. Discovery of a Novel Small-Molecule Modulator of C-X-C Chemokine Receptor Type 7 as a treatment, for Cardiac Fibrosis. J Med Chem. 2018 Apr 26;61(8):3685-3696.
Menhaji-Klotz E, et al. Discovery of a Novel Small-Molecule Modulator of C-X-C Chemokine Receptor Type 7 as a treatment, for Cardiac Fibrosis. J Med Chem. 2018 Apr 26;61(8):3685-3696.

Other Notes

Small volumes of CXCR7, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CXCR7 purchase

MBS5752960 is an inhibitor targeting CXCR7. Also known as CXCR7 modulator 2.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000