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DC1SMe Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752987

DC1 is an ADC cytotoxin, similar to the small groove-binding DNA alkylating agent CC-1065. DC1 can be used to synthesize antibody-drug conjugates targeted to the treatment,of cancer. DC1Sme is a DC1 derivative with IC50 values of Ramos, Namalwa, HL60/s and… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DC1SMe, Inhibitor
Full Product Name
DC1SMe
Product Gene Name
DC1SMe, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
684.23
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C35H30ClN5O4S2
SMILES
O=C(C(N1)=CC2=C1C=CC(NC(CCSSC)=O)=C2)NC3=CC4=C(NC(C(N5C[C@@H](CCl)C6=C5C=C(O)C7=CC=CC=C67)=O)=C4)C=C3
CAS Number
501666-85-9
Target & IC50
Others

Structure of DC1SMe, inhibitor

DC1SMe Inhibitor – Cat# MBS5752987

Product References and Citations for DC1SMe, inhibitor

Zhao RY, et al. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment,of cancer. J Med Chem. 2012 Jan 26;55(2):766-82.
Zhao RY, et al. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment,of cancer. J Med Chem. 2012 Jan 26;55(2):766-82.

Other Notes

Small volumes of DC1SMe, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DC1SMe purchase

MBS5752987 is an inhibitor targeting DC1SMe.
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