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Desmethyl ferroquine Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753004

Desmethyl ferroquine is the active and major metabolite of Ferroquine.Desmethyl ferroquine shows significant activity against Chloroquine-susceptible and resistant P. falciparum strains. Ferroquine is an antimalarial. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Desmethyl ferroquine, Inhibitor
Full Product Name
Desmethyl ferroquine
Product Synonym Names
SSR97213
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
419.73
Solubility
DMSO: 2.5mg/mL (5.96mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C22H22ClFeN3
SMILES
CNCC12=[CH]3[Fe+2]1456789([CH-]%10[CH]6=[CH]7[CH]8=[CH]9%10)[C-]2([CH]4=[CH]53)CNC%11=CC=NC%12=C%11C=CC(Cl)=C%12
CAS Number
903546-18-9
Target & IC50
Others
In Vitro
Ferroquine's apparent terminal half-life is estimated to be 15.9 days. However, the main metabolite of the same activity, desmethyl ironquine (DMFQ), has a longer t1/2z, and the total average estimated time is 31.4 days.

Structure of Desmethyl ferroquine, inhibitor

Desmethyl ferroquine Inhibitor – Cat# MBS5753004

Product References and Citations for Desmethyl ferroquine, inhibitor

Supan C, et al. Pharmacokinetics of ferroquine, a novel 4-aminoquinoline, in asymptomatic carriers of Plasmodium falciparum infections. Antimicrob Agents Chemother. 2012 Jun;56(6):3165-73.
Supan C, et al. Pharmacokinetics of ferroquine, a novel 4-aminoquinoline, in asymptomatic carriers of Plasmodium falciparum infections. Antimicrob Agents Chemother. 2012 Jun;56(6):3165-73.

Other Notes

Small volumes of Desmethyl ferroquine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Desmethyl ferroquine purchase

MBS5753004 is an inhibitor targeting Desmethyl ferroquine.
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