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DFP00173 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753008

DFP00173 is a potent and selective aquaporin 3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with IC50 of ~0.1-0.4uM. Compared with the homologous AQP subtypes AQP7 and AQP9, DFP00173 is selective for AQP3. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DFP00173, Inhibitor
Full Product Name
DFP00173
Product Gene Name
DFP00173, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
332.16
Solubility
DMSO: 125mg/mL (376.32mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C11H7Cl2N3O3S
SMILES
O=C(NC1=CSC([N+]([O-])=O)=C1)NC2=C(Cl)C=CC=C2Cl
CAS Number
672286-03-2
Target & IC50
Others

Structure of DFP00173, inhibitor

DFP00173 Inhibitor – Cat# MBS5753008

Product References and Citations for DFP00173, inhibitor

Sonntag Y, et al. Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors, J Biol Chem. 2019 May 3;294(18):7377-7387.
Sonntag Y, et al. Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors, J Biol Chem. 2019 May 3;294(18):7377-7387.

Other Notes

Small volumes of DFP00173, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DFP00173 purchase

MBS5753008 is an inhibitor targeting DFP00173.
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