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DRI-C21045 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753045

Dri-c21045 showed concentration-dependent inhibition of NF- B activation and all CD40L induced by B cell proliferation. IC50 was 17.1 M and 4.5 M, respectively.Dri-c21045 is an effective selective inhibitor of CD40-CD40L synergistic stimulator protein-protein… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DRI-C21045, Inhibitor
Full Product Name
DRI-C21045
Product Gene Name
DRI-C21045, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
580.61
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C32H24N2O7S
SMILES
O=S(C1=CC=CC2=CC=CC(NC(C3=CC=C(C4=CC=C(NC(C5=CC=C(C(OC)=O)C=C5)=O)C=C4)C=C3)=O)=C21)(O)=O
CAS Number
2101765-81-3
Target & IC50
CD40: ic50 0.17uM

Structure of DRI-C21045, inhibitor

DRI-C21045 Inhibitor – Cat# MBS5753045

Product References and Citations for DRI-C21045, inhibitor

Chen J, et al. Small-Molecule Inhibitors of the CD40-CD40L Costimulatory Protein-Protein Interaction. J Med Chem. 2017 Nov 9;60(21):8906-8922.
Chen J, et al. Small-Molecule Inhibitors of the CD40-CD40L Costimulatory Protein-Protein Interaction. J Med Chem. 2017 Nov 9;60(21):8906-8922.

Other Notes

Small volumes of DRI-C21045, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DRI-C21045 purchase

MBS5753045 is an inhibitor targeting DRI-C21045.
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