DUB-IN-3 Inhibitor

Name: DUB-IN-3 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753052
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753052

DUB-IN-3 is IC50 of 0.56uM for USP8,is a potent deubiquitinase (USP) enzyme inhibitor extracted from reference compound 22c. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

DUB-IN-3, Inhibitor

Full Product Name

DUB-IN-3

Product Gene Name

DUB-IN-3, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

287.28

Solubility

DMSO: 25mg/mL (87.02mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C16H9N5O

SMILES

C=CCO/N=C1C2=C(N=C(C#N)C(C#N)=N2)C3=CC=CC=C/13

CAS Number

924296-17-3

Target & IC50

USP8: ic50 0.56uM

Product Categories/Family for DUB-IN-3, inhibitor

Ubiquitination; DUB

Product References and Citations for DUB-IN-3, inhibitor

Colombo M, et al. Synthesis and biological evaluation of 9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile analogues as potential inhibitors of deubiquitinating enzymes. ChemMedChem. 2010 Apr 6;5(4):552-8.
Colombo M, et al. Synthesis and biological evaluation of 9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile analogues as potential inhibitors of deubiquitinating enzymes. ChemMedChem. 2010 Apr 6;5(4):552-8.

Other Notes

Small volumes of DUB-IN-3, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DUB-IN-3 purchase

MBS5753052 is an inhibitor targeting DUB-IN-3.