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Eliglustat hemitartrate Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753083

Eliglustat Hemitartrate, with an IC50 of 24nM, is a specific, potent, oral active glucocerebral glycosidase inhibitor. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Eliglustat hemitartrate, Inhibitor
Full Product Name
Eliglustat hemitartrate
Product Synonym Names
Genz-112638; Eliglustat tartrate
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
959.17
Solubility
H2O: 50mg/mL (52.13mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C50H78N4O14
SMILES
CCCCCCCC(N[C@H](CN1CCCC1)[C@@H](C2=CC=C(OCCO3)C3=C2)O)=O.CCCCCCCC(N[C@H](CN4CCCC4)[C@@H](C5=CC=C(OCCO6)C6=C5)O)=O.O=C(O)[C@H](O)[C@@H](O)C(O)=O
CAS Number
928659-70-5
Target & IC50
glucocerebroside synthase: ic50 24nM
In Vitro
Mice that received drug prior to significant accumulation of substrate (10 weeks of age) showed reduced levels of glucosylceramide and number of Gaucher cells in the spleen, lung and liver when compared to age-matched control animals.

Structure of Eliglustat hemitartrate, inhibitor

Eliglustat hemitartrate Inhibitor – Cat# MBS5753083

Product References and Citations for Eliglustat hemitartrate, inhibitor

McEachern KA, et al. A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy ofGaucher disease. Mol Genet Metab. 2007 Jul;91(3):259-67.
McEachern KA, et al. A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy ofGaucher disease. Mol Genet Metab. 2007 Jul;91(3):259-67.

Other Notes

Small volumes of Eliglustat hemitartrate, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Eliglustat hemitartrate purchase

MBS5753083 is an inhibitor targeting Eliglustat hemitartrate.
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