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Emixustat Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753089

Emixustat, is an inhibitor of the visual cycle isomerase with an IC50 value of 4.4nM in vitro. a novel visual cycle modulator. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Emixustat, Inhibitor
Full Product Name
Emixustat
Product Synonym Names
ACU-4429
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
263.38
Solubility
DMSO: 43mg/mL (163.26mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C16H25NO2
SMILES
O[C@H](CCN)C1=CC(OCC2CCCCC2)=CC=C1
CAS Number
1141777-14-1
Target & IC50
visual cycle isomerase: ic50 4.4nM

Structure of Emixustat, inhibitor

Emixustat Inhibitor – Cat# MBS5753089

Product References and Citations for Emixustat, inhibitor

Bavik C, et al. Visual Cycle Modulation as an Approach toward Preservation of Retinal Integrity. PLoS One. 2015 May 13;10(5):e0124940.
Bavik C, et al. Visual Cycle Modulation as an Approach toward Preservation of Retinal Integrity. PLoS One. 2015 May 13;10(5):e0124940.
Kiser PD, et al. Catalytic mechanism of a retinoid isomerase essential for vertebrate vision. Nat Chem Biol. 2015 Jun;11(6):409-15.
Kiser PD, et al. Catalytic mechanism of a retinoid isomerase essential for vertebrate vision. Nat Chem Biol. 2015 Jun;11(6):409-15.

Other Notes

Small volumes of Emixustat, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Emixustat purchase

MBS5753089 is an inhibitor targeting Emixustat.
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