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Fumarate hydratase-IN-2 sodium salt Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753146

Fumarate hydratase-IN-2 sodium salt is a cell-permeable and competitive fumarate hydratase inhibitor (Ki=4.5uM) with nutrient-dependent cytotoxicity. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Fumarate hydratase-IN-2 sodium salt, Inhibitor
Full Product Name
Fumarate hydratase-IN-2 sodium salt
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
440.47
Solubility
DMSO: 10.66mg/mL (24.20mM) Need ultrasonic and warming
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C25H25N2NaO4
SMILES
O=C([O-])[C@]1([C@H](CC(NC)=O)C2=O)C(N2CC(C=C3)=CC=C3C4=CC=CC=C4)=CCCC1.[Na+]
Target & IC50
Fumarate hydratase(ki): ic50 4.5uM (ki)

Structure of Fumarate hydratase-IN-2 sodium salt, inhibitor

Fumarate hydratase-IN-2 sodium salt Inhibitor – Cat# MBS5753146

Product References and Citations for Fumarate hydratase-IN-2 sodium salt, inhibitor

Takeuchi T et al. Identification of fumarate hydratase inhibitors with nutrient-dependent cytotoxicity. J Am Chem Soc. 2015 Jan 21;137(2):564-7.
Takeuchi T et al. Identification of fumarate hydratase inhibitors with nutrient-dependent cytotoxicity. J Am Chem Soc. 2015 Jan 21;137(2):564-7.

Other Notes

Small volumes of Fumarate hydratase-IN-2 sodium salt, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Fumarate hydratase-IN-2 sodium salt purchase

MBS5753146 is an inhibitor targeting Fumarate hydratase-IN-2 sodium salt.
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