gamma-Secretase Modulators Inhibitor

gamma-Secretase Modulators is useful for Alzheimer's disease. IC50 value: Target: gamma-secretase modulator.gamma-Secretase Modulators (Amyloid-beta production inhibitor) is a Amyloid-beta production inhibitor.

Watahiki H, Yagishita S, Futai E, Ishiura S.CTF1-51, a truncated carboxyl-terminal fragment of amyloid precursor protein, suppresses the effects of Abeta42-lowering gamma-secretase modulators.Neurosci Lett. 2012 Sep 27;526(2):96-9. Epub 2012 Aug 23.
Watahiki H, Yagishita S, Futai E, Ishiura S.CTF1-51, a truncated carboxyl-terminal fragment of amyloid precursor protein, suppresses the effects of Abeta42-lowering gamma-secretase modulators.Neurosci Lett. 2012 Sep 27;526(2):96-9. Epub 2012 Aug 23.
Wanngren J, Ottervald J, Parpal S, Portelius E, Stromberg K, Borgegord T, Klintenberg R, Jureus A, Blomqvist J, Blennow K, Zetterberg H, Lundkvist J, Rosqvist S, Karlstrom H.Second generation gamma-secretase modulators exhibit different modulation of Notch beta
Wanngren J, Ottervald J, Parpal S, Portelius E, Stromberg K, Borgegord T, Klintenberg R, Jureus A, Blomqvist J, Blennow K, Zetterberg H, Lundkvist J, Rosqvist S, Karlstrom H.Second generation gamma-secretase modulators exhibit different modulation of Notch beta
Wagner SL, Tanzi RE, Mobley WC, Galasko D.Potential Use of gamma-Secretase Modulators in the treatment,of Alzheimer Disease. Arch Neurol. 2012 Jul 16:1-4.
Wagner SL, Tanzi RE, Mobley WC, Galasko D.Potential Use of gamma-Secretase Modulators in the treatment,of Alzheimer Disease. Arch Neurol. 2012 Jul 16:1-4.
Bulic B, Ness J, Hahn S, Rennhack A, Jumpertz T, Weggen S.Chemical Biology, Molecular Mechanism and Clinical Perspective of gamma-Secretase Modulators in Alzheimer's Disease.Curr Neuropharmacol. 2011 Dec;9(4):598-622.
Bulic B, Ness J, Hahn S, Rennhack A, Jumpertz T, Weggen S.Chemical Biology, Molecular Mechanism and Clinical Perspective of gamma-Secretase Modulators in Alzheimer's Disease.Curr Neuropharmacol. 2011 Dec;9(4):598-622.
Kretner, Benedikt; Fukumori, Akio; Gutsmiedl, Amelie; Page, Richard M.; Luebbers, Thomas; Galley, Guido; Baumann, Karlheinz; Haass, Christian; Steiner, Harald. Attenuated A. Beta.42 Responses to Low Potency.gamma.-Secretase Modulators Can Be Overcome for
Kretner, Benedikt; Fukumori, Akio; Gutsmiedl, Amelie; Page, Richard M.; Luebbers, Thomas; Galley, Guido; Baumann, Karlheinz; Haass, Christian; Steiner, Harald. Attenuated A. Beta.42 Responses to Low Potency.gamma.-Secretase Modulators Can Be Overcome for

Small volumes of gamma-Secretase Modulators, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5753165 is an inhibitor targeting gamma-Secretase Modulators.