GSK-3beta Inhibitor – 1

Name: GSK-3beta Inhibitor; 1; MyBioSource
Brand: MyBioSource
SKU: MBS5753227
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753227

GSK-3beta inhibitor 1 is an inhibitor of GSK-3beta(IC50 of 4.9nM) and demonstrates high antidiabetic efficacy. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GSK-3beta 1, Inhibitor

Full Product Name

GSK-3beta inhibitor 1

Product Gene Name

GSK-3beta, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

222.24

Solubility

DMSO: 30mg/mL (134.99mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C14H10N2O

SMILES

O=C1Nc2ccccc2\C1=C\c1ccccn1

CAS Number

187325-53-7

Target & IC50

GSK-3beta: ic50 4.9nM

Product Categories/Family for GSK-3beta, inhibitor

PI3K/Akt/mTOR signaling; GSK-3; Stem Cells

Product References and Citations for GSK-3beta, inhibitor

Lozinskaya NA, et al. Synthesis and biological evaluation of 3-substituted 2-oxindole derivatives as new glycogen synthase kinase 3beta inhibitors. Bioorg Med Chem. 2019 May 1;27(9):1804-1817.
Lozinskaya NA, et al. Synthesis and biological evaluation of 3-substituted 2-oxindole derivatives as new glycogen synthase kinase 3beta inhibitors. Bioorg Med Chem. 2019 May 1;27(9):1804-1817.

Other Notes

Small volumes of GSK-3beta, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSK-3beta purchase

MBS5753227 is an inhibitor targeting GSK-3beta. Also known as GSK-3beta inhibitor 1.