GSK-843 Inhibitor

Name: GSK-843 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753234
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753234

GSK-843 is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor (IC50: 8.6nM for binding RIP3 kinase domain; IC50: 6.5nM for inhibiting kinase activity). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GSK-843, Inhibitor

Full Product Name

GSK-843

Product Gene Name

GSK-843, inhibitor

Product Synonym Names

GSK'843

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

377.49

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C19H15N5S2

SMILES

NC1=NC=C(C2=CC(C)=NN2C)C3=C1C(C4=CC=C(SC=N5)C5=C4)=CS3

CAS Number

1601496-05-2

Target & IC50

RIP3: ic50 6.5nM

Product Categories/Family for GSK-843, inhibitor

Apoptosis; TNF

Product References and Citations for GSK-843, inhibitor

Mandal P, et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. Mol Cell. 2014 Nov 20;56(4):481-95.
Mandal P, et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. Mol Cell. 2014 Nov 20;56(4):481-95.

Other Notes

Small volumes of GSK-843, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSK-843 purchase

MBS5753234 is an inhibitor targeting GSK-843.