GSK2593074A Inhibitor

Name: GSK2593074A Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753241
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753241

GSK2593074A is a necroptosis inhibitor for dual-targeting to both RIP1 and RIP3. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GSK2593074A, Inhibitor

Full Product Name

GSK2593074A

Product Gene Name

GSK2593074A, inhibitor

Product Synonym Names

GSK'074

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

465.57

Solubility

DMSO: 41.67mg/mL (89.50mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C27H23N5OS

SMILES

CN1N=CC(C2=CN=C(N)C3=C2SC=C3C4=CC5=C(N(C(CC6=CC=CC=C6)=O)CC5)C=C4)=C1

CAS Number

1337531-06-2

Target & IC50

RIP1

Product Categories/Family for GSK2593074A, inhibitor

Apoptosis; TNF

Product References and Citations for GSK2593074A, inhibitor

Zhou T, et al. Identification of a novel class of RIP1/RIP3 dual inhibitors that impede cell death and inflammation in mouse abdominal aortic aneurysm models. Cell Death Dis. 2019 Mar 6;10(3):226.
Zhou T, et al. Identification of a novel class of RIP1/RIP3 dual inhibitors that impede cell death and inflammation in mouse abdominal aortic aneurysm models. Cell Death Dis. 2019 Mar 6;10(3):226.

Other Notes

Small volumes of GSK2593074A, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSK2593074A purchase

MBS5753241 is an inhibitor targeting GSK2593074A.