Encequidar mesylate Inhibitor

Name: Encequidar mesylate Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753289
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753289

MBS5753289 is an inhibitor targeting Encequidar mesylate. Encequidar mesylate is a competitive P-glycoprotein inhibitor. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Encequidar mesylate, Inhibitor

Full Product Name

Encequidar mesylate

Product Synonym Names

HM30181 mesylate; HM30181A mesylate

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

784.83

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C39H40N6O10S

SMILES

O=C(C1=CC(C2=CC=CC=C2O1)=O)NC3=CC(OC)=C(OC)C=C3C4=NN(C5=CC=C(CCN6CC7=C(C=C(OC)C(OC)=C7)CC6)C=C5)N=N4.CS(=O)(O)=O

CAS Number

849675-87-2

Target & IC50

P-glycoprotein

In Vitro

treatment of 0.1 or 1nM Encequidar lead to 20 and 42% inhibition of survival at the 100nM and 1000nM NSC 125973 treatment, respectively.

Product References and Citations for Encequidar mesylate, inhibitor

Kim JC, et al. Effect of HM30181 mesylate salt-loaded microcapsules on the oral absorption of NSC 125973 as a novel P-glycoprotein inhibitor. Int J Pharm. 2016 Jun 15;506(1-2):93-101.
Kim JC, et al. Effect of HM30181 mesylate salt-loaded microcapsules on the oral absorption of NSC 125973 as a novel P-glycoprotein inhibitor. Int J Pharm. 2016 Jun 15;506(1-2):93-101.
Joo KM, et al. Response of brain specific microenvironment to P-glycoprotein inhibitor: an important factor determining therapeutic effect of P-glycoprotein inhibitor on brain metastatic tumors. Int J Oncol. 2008 Oct;33(4):705-12.
Joo KM, et al. Response of brain specific microenvironment to P-glycoprotein inhibitor: an important factor determining therapeutic effect of P-glycoprotein inhibitor on brain metastatic tumors. Int J Oncol. 2008 Oct;33(4):705-12.

Other Notes

Small volumes of Encequidar mesylate, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Encequidar mesylate Inhibitor

Product Overview

Structure of Encequidar mesylate, inhibitor

Related Product Information for Encequidar mesylate, inhibitor

Product References and Citations for Encequidar mesylate, inhibitor

Other Notes