iFSP1 Inhibitor

Name: iFSP1 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753315
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753315

iFSP1 is able to sensitize a variety of human cancer cell lines to the ferroptosis inducer, such as (1S,3R)-RSL3.iFSP1 is a potent, selective and glutathione-independent inhibitor of ferroptosis suppressor protein 1 (FSP1) (AIFM2) with an EC50 of 103nM. iFSP1… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

iFSP1, Inhibitor

Full Product Name

iFSP1

Product Gene Name

iFSP1, inhibitor

Form/Format

Solid. Powder

Purity/Purification

99.74%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

323.35

Solubility

DMSO: 25mg/mL (77.32mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C20H13N5

SMILES

Cc1ccc(cc1)-c1c(C#N)c(N)n2c3ccccc3nc2c1C#N

CAS Number

150651-39-1

Target & IC50

Ferroptosis

Product Categories/Family for iFSP1, inhibitor

Cell Cycle/Checkpoint; Ferroptosis

Product References and Citations for iFSP1, inhibitor

Doll S, et al. FSP1 is a glutathione-independent ferroptosis suppressor.Nature. 2019 Nov;575(7784):693-698.
Doll S, et al. FSP1 is a glutathione-independent ferroptosis suppressor.Nature. 2019 Nov;575(7784):693-698.

Other Notes

Small volumes of iFSP1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for iFSP1 purchase

MBS5753315 is an inhibitor targeting iFSP1.