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JI051 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753347

JI051,Anti-cancer activity. is a stabilizer for the Hes1-PHB2 interaction, interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
JI051, Inhibitor
Full Product Name
JI051
Product Gene Name
JI051, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
364.44
Solubility
DMSO: 125mg/mL (342.99mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C22H24N2O3
SMILES
O=C(NCCC1=CC=CC=C1OCC)/C=C/C2=CNC3=C2C=CC=C3OC
CAS Number
2234281-75-3
Target & IC50
Others

Structure of JI051, inhibitor

JI051 Inhibitor – Cat# MBS5753347

Product References and Citations for JI051, inhibitor

Perron A, et al. Small-molecule screening yields a compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone. J Biol Chem. 2018 May 25;293(21):8285-8294.

Other Notes

Small volumes of JI051, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for JI051 purchase

MBS5753347 is an inhibitor targeting JI051.
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