KI696 Inhibitor

Name: KI696 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753368
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753368

KI696 is an effective and selective inhibitor of KEAP1/NRF2 interaction. KI696 is a high-affinity probe that disrupts the Keap1/NRF2 interaction. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

KI696, Inhibitor

Full Product Name

KI696

Product Gene Name

KI696, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

550.63

Solubility

DMSO: 125mg/mL (227.01mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C28H30N4O6S

SMILES

COC1=C(N2C)C(N=N2)=CC([C@H](C3=CC(CN(C[C@H]4C)S(=O)(C5=CC=CC=C5O4)=O)=C(C)C=C3)CC(O)=O)=C1

CAS Number

1799974-70-1

Target & IC50

Keap1-NRF2

Product Categories/Family for KI696, inhibitor

Metabolism; Others

Product References and Citations for KI696, inhibitor

Davies TG, et al. Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery. J Med Chem. 2016 Apr 28;59(8):3991-4006.
Davies TG, et al. Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery. J Med Chem. 2016 Apr 28;59(8):3991-4006.

Other Notes

Small volumes of KI696, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KI696 purchase

MBS5753368 is an inhibitor targeting KI696.