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LDC7559 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753397

LDC7559 via blocking neutrophil extracellular trap (NET) in the late stages. Implement inhibition gasdermin D (GSDMD). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LDC7559, Inhibitor
Full Product Name
LDC7559
Product Gene Name
LDC7559, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
349.38
Solubility
DMSO: 125mg/mL (357.78mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C20H19N3O3
SMILES
COC1=C(C=CC=C1)C2=NN3C(COC(C=C(NC(C)=O)C=C4)=C4C3)=C2
Target & IC50
Gasdermin D

Structure of LDC7559, inhibitor

LDC7559 Inhibitor – Cat# MBS5753397

Product References and Citations for LDC7559, inhibitor

Spel L, et al. Gasdermin D opens the way for NETs. Nat Rev Rheumatol. 2018 Dec;14(12):690-692.
Spel L, et al. Gasdermin D opens the way for NETs. Nat Rev Rheumatol. 2018 Dec;14(12):690-692.
Sollberger G, et al. Gasdermin D plays a vital role in the generation of neutrophil extracellular traps. Sci Immunol. 2018 Aug 24;3(26). pii: eaar6689.
Sollberger G, et al. Gasdermin D plays a vital role in the generation of neutrophil extracellular traps. Sci Immunol. 2018 Aug 24;3(26). pii: eaar6689.

Other Notes

Small volumes of LDC7559, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LDC7559 purchase

MBS5753397 is an inhibitor targeting LDC7559.
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