LHVS Inhibitor

Name: LHVS Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753409
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753409

LHVS effectively blocks T. gondii microneme protein secretion (IC50=10uM), gliding motility, and cell invasion. LHVS is a potent, non-selective cysteine protease inhibitor. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LHVS, Inhibitor

Full Product Name

LHVS

Product Gene Name

LHVS, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

527.68

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C28H37N3O5S

SMILES

O=C(N1CCOCC1)N[C@H](C(N[C@@H](CCC2=CC=CC=C2)/C=C/S(=O)(C3=CC=CC=C3)=O)=O)CC(C)C

CAS Number

170111-28-1

Target & IC50

Cysteine protease

Product Categories/Family for LHVS, inhibitor

Proteases/Proteasome; Cysteine Protease

Product References and Citations for LHVS, inhibitor

Wilson SR, et al. Cathepsin K activity-dependent regulation of osteoclast actin ring formation and bone resorption. J Biol Chem. 2009 Jan 23;284(4):2584-92.
Wilson SR, et al. Cathepsin K activity-dependent regulation of osteoclast actin ring formation and bone resorption. J Biol Chem. 2009 Jan 23;284(4):2584-92.
Teo CF, et al.Cysteine protease inhibitors block Toxoplasma gondii microneme secretion and cell invasion. Antimicrob Agents Chemother. 2007 Feb;51(2):679-88.
Teo CF, et al.Cysteine protease inhibitors block Toxoplasma gondii microneme secretion and cell invasion. Antimicrob Agents Chemother. 2007 Feb;51(2):679-88.

Other Notes

Small volumes of LHVS, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LHVS purchase

MBS5753409 is an inhibitor targeting LHVS.