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LTV-1 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753429

LTV-1 has the potential for autoimmunity treatment, LTV-1 is a potent lymphoid tyrosine phosphatase (LYP) inhibitor in T cells with an IC50 of 508nM. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LTV-1, Inhibitor
Full Product Name
LTV-1
Product Gene Name
LTV-1, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
472.51
Solubility
DMSO: 50mg/mL (105.82mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C26H20N2O5S
SMILES
O=C(O)C1=CC=CC(COC2=CC=C(/C=C(C(N3C4=CC=CC=C4C)=O)\C(NC3=S)=O)C=C2)=C1
CAS Number
347379-29-7
Target & IC50
LYP, in T cells: ic50 508nM

Structure of LTV-1, inhibitor

LTV-1 Inhibitor – Cat# MBS5753429

Product References and Citations for LTV-1, inhibitor

Vang T, et al. LYP inhibits T-cell activation when dissociated from CSK. Nat Chem Biol. 2012 Mar 18;8(5):437-446.
Vang T, et al. LYP inhibits T-cell activation when dissociated from CSK. Nat Chem Biol. 2012 Mar 18;8(5):437-446.

Other Notes

Small volumes of LTV-1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LTV-1 purchase

MBS5753429 is an inhibitor targeting LTV-1.
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