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LysRs-IN-2 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753445

LysRs-IN-2 is a lysyl-tRNA synthetase (KRS) inhibitor with IC50s of 0.13uM and 0.015uM for Cryptosporidium parvum lysyl-tRNA synthetase (CpKRS) and Plasmodium falciparum lysyl-tRNA synthetase (PfKRS), respectively. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LysRs-IN-2, Inhibitor
Full Product Name
LysRs-IN-2
Product Gene Name
LysRs-IN-2, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
355.31
Solubility
DMSO: 60mg/mL (168.87mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C17H16F3NO4
SMILES
FC1=CC=C(OC(C(NCC2(O)CCC(F)(F)CC2)=O)=CC3=O)C3=C1
CAS Number
2170696-76-9
Target & IC50
PfKRS: ic50 0.015uM
CpKRS: ic50 0.13uM

Structure of LysRs-IN-2, inhibitor

LysRs-IN-2 Inhibitor – Cat# MBS5753445

Product References and Citations for LysRs-IN-2, inhibitor

Baragana B, et al. Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7015-7020.
Baragana B, et al. Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7015-7020.

Other Notes

Small volumes of LysRs-IN-2, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LysRs-IN-2 purchase

MBS5753445 is an inhibitor targeting LysRs-IN-2.
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